Current Research:

  • Comparative analysis of leprosy causes type 1 & type 2 genes
  • Insilco characterization and analysis of RB1 gene
  • Identification of suitable ligand for molecular docking of pancreatic cancer
  • An in-silico studies on the Interaction of Antxr1 with protective antigen(toxin)
  • Identification of suitable ligand for molecular docking of Rheumatic Heart Disease using combinatorial chemistry
  • Structure prediction for the protein product of SIVA1 gene- Homology modelling approach.
  • Structure prediction for the 3 beta-hydroxysteroid dehydrogenase- Homology modelling approach.
  • Docking studies on the binding site of receptor -BRCA1 and screening its suitable ligands

Research Findings:

  • Identification of drug targets using protein docking – Huntington disease
  • Homology modeling and effective inhibitor for cystinosis disease
  • Analysis of DJ-1 gene in the pathogenesis of parkinson’s disease
  • Comparative genomics account on the lysine biosynthesis pathway
  • Insilico analysis of the Ataxia telangiectasia mutated (ATM) gene and its genetic node for the determination of its role in breast cancer
  • Homology modeling of hemlysin precursor protein – HmpB of rheumatoid arthritis using modeler
  • Identification of microbial genes and gene products responsile for biofuel ethanol production using bioinformatics tools and databases
  • The analysis of Rna Interface in treating Parkinson’s disease
  • To interpret the genomic relationship of Homo sapiens with Pan troglodytes at the central dogma level via codon usage comparison.
  • To elucidate the genomic relationship of Bacillus subtilis with Bacillus amyloliquefaciens at the central dogma level via codon usage comparison
  • Docking efficacy assessment of few cox inhibitors and its halogenated analogs
  • Molecular signature and protein expression with reference to genetic programming of cells
  • Homology modeling of transferin protein and its molecular recognition study using HEX docking tool
  • Homology modeling of GPC protein and its hydropathy profile study”, “virtual screening of HIV 1 integrase inhibitor
  • Neurocutaneous interaction – an approach in systems biology
  • Structure Prediction of Mucus secretion (fish) in defining the toxicity activities.
  • Structure Modeling of Neuraminidase Protein
  • Secondary Structure Prediction using Fold - Recognition.
  • Molecular Signature and Protein Expression with reference to Genetic programming of cells.
  • Homology Modeling Of GPCR Protein and its hydropath profile study.
  • Neuro Cutaneous Disease, an approach in Systems Biology.
  • Analysis of Tp53 gene.
  • Homology Modeling of Transferrin Protein and its molecular recognition study using Hex - Docking tool.
  • Gene Prediction for Cystic-Fibrosis and Canavan Diseases
  • Evolutionary Genetics of Cyanobacteria
  • Comparative Genomics of ATF2 gene
  • Comparative Genomics of Mushrooms
  • Comparative Genomics of the gene in Acute Myeloid Leukemia
  • Microbial Genomics of Food Poisoning bacteria
  • Microbial Genomics of Oil Bio-degradation microbes
  • Colon Caner & MODY – System Biology approach
  • Docking study about SPARC protein
  • Docking study of Orphan Nuclear receptor
  • Colon Cancer – Computer Aided Drug Designing
  • System Biology and Docking study about A therosclerosis